Low‐Dose Interleukin‐2 for Refractory Autoimmune Hepatitis
نویسندگان
چکیده
منابع مشابه
Autoimmune hepatitis
Autoimmune hepatitis is (AIH) is a chronic hepatitis that occurs in children and adults of all ages. It is characterized by immunologic and autoimmune features, including circulating auto antibodies and high serum globulin concentrations. It was first described in the 1950s by term of chronic active hepatitis. It has 2 types with different auto antibodies. Diagnosis is based upon serologic and ...
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A 44-year-old woman was found to have elevated aminotransferases, twice the upper limit of normal. Liver biopsy demonstrated a mixed inflammatory process suggestive of both primary biliary cirrhosis and autoimmune hepatitis (AIH). Prednisone and azathioprine were started, with normalization of aminotransferases. Six months later, she returned with worsening pruritus and re-evaluation demonstrat...
متن کاملSuccessful treatment of refractory autoimmune hepatitis with rituximab.
Autoimmune hepatitis is a severe liver disease in which ~10% of patients do not respond to standard treatment. We describe a new rescue therapy using anti-CD20 monoclonal antibodies (rituximab). Complete remission was obtained and maintained by using low doses of immunosuppressive drugs with repeated anti-CD20 infusions.
متن کاملSuccessful Treatment of Refractory Autoimmune Hepatitis With Rituximab
Autoimmune hepatitis is a severe liver disease in which ∼10% of patients do not respond to standard treatment. We describe a new rescue therapy using anti-CD20 monoclonal antibodies (rituximab). Complete remission was obtained and maintained by using low doses of immunosuppressive drugs with repeated anti-CD20 infusions. Pediatrics 2013;132:e526–e530 AUTHORS: Daniel D’Agostino, MD,a Alejandro C...
متن کاملSuccessful Treatment of Refractory Autoimmune Hepatitis With Rituximab
Autoimmune hepatitis is a severe liver disease in which ∼10% of patients do not respond to standard treatment. We describe a new rescue therapy using anti-CD20 monoclonal antibodies (rituximab). Complete remission was obtained and maintained by using low doses of immunosuppressive drugs with repeated anti-CD20 infusions. Pediatrics 2013;132:e526–e530 AUTHORS: Daniel D’Agostino, MD,a Alejandro C...
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ژورنال
عنوان ژورنال: Hepatology
سال: 2018
ISSN: 0270-9139,1527-3350
DOI: 10.1002/hep.30059